摘要
Abstract
ABSTRACTObjective:To evaluate the curative effects of 4 kinds of eradication therapy ofHelicobacterpylori (Hp)infection and explore the new way of eradication therapy of Hp infection.Methods:About 240 patients with peptic ulcer caused by Hp infection, who were diagnosed by13C - urea breath test(13C - UBT)or rapid urease test of gastric mucosa biopsy(RUT)and electronic gastroscopy in our hospital in 2014, were selected according to se-quence table and randomly divided into A, B, C and D groups, 60 cases in each group. Group A was given rabeprazole combined with amoxicillin and clarithromycin, group B was given rabeprazole combined with amoxi-cillin and levofloxacin, group C was treated with rabeprazole combined with bismuth potassium citrate, amoxicillin and furazolidone and group D was treated with rabeprazole combined with amoxicillin, clarithromycin and Bifid triple viable capsules dissolving at intestines, and the whole course of treatment was 14 days. To compare 4 kinds of therapy for Hp eradication rate.Results:The Hp eradication rates of 4 groups were 73.3%, 76.7%, 93.3% and 90.0%, the curative effects between groups A and B and between groups C and D had no significant differences (P>0.05), but there were significant differences in groups A, B and groups C, D(P<0.05).Conclusion:The Hp eradication rates of the conventional triple therapy and triple therapy with levofloxacin were not ideal, but the combined use with bismuth preparation and the standard dose of probiotics can significantly improve the Hp eradication rate. It may serve as a new way of treatment of Hp infection.关键词
幽门螺杆菌/幽门螺杆菌根除率/疗效分析/铋制剂/微生态制剂Key words
Helicobacterpylori/Eradication Rate ofHelicobacterpylori/Efficacy Analysis/Bismuth Preparation/Probiotics
