摘要
Abstract
Objective:Through providing pharmaceutical care to the children with chronic cough and their families to improve the therapeutic effects of chronic cough and promote rational use of drugs.Methods:A total of 182 children aged 0 ~14 years old,who were diagnosed as chronic cough in our hospital during the second half of 2013,were divided into cough variant asthma(CVA),upper airway cough syndrome(UACS)and post infection cough(PIC)groups by the causes of cough and number of patients in each group was 69,62 and 51 respectively. Each group was randomly divided into experimental group and control group. The experimental groups received not only conventional treatment but also pharmaceutical care intervention,including questionnaire design and fulfillment,education before treatment,the establishment of drug record,feedback to the doctors,outpatient counseling and telephone follow-up for patients. The control groups only received conventional treatment. Investigation and analysis of the experimental and control groups were made on the medication use,times of outpatient and emergency visits upon outbreak of disease and the total medication expenses.Results:In CVA group,oral antibiotics consumption rate decreased to 0.00% after three month intervention by pharmaceutical care, which was significantly lower than that in control group(21.74%)with the statistical significance ofP< 0.05. The utilization of inhaled corticosteroids in experimental group was 100.00% through the period of pharmaceutical care,which was higher than that in control group(30.43%)(P< 0.05). In UACS group,the utilization rate of oral antibiotics in intervention group decreased to 0.00%,which was much lower than that in control group(26.83%) (P< 0.05). The utilization rates of inhaled corticosteroids in experimental group increased to 38.10% and 47.62% after one and three month interventions of pharmaceutical care,while there were only 12.2% and 9.76% in control group(P< 0.05). In PIC group,the usage rate of oral antibiotics decreased to 0.00% after three month intervention of pharmaceutical care and 31.25% in control group(P< 0.05). The utilization rate of inhaled corticosteroids in experimental group increased to 47.37% after one month of the drug administration and which was 9.38% in control group(P< 0.05). In all three experimental groups,the frequency of outpatient visits and the total medication expenses were much lower than those in control groups,and there was a statistical significance between the experimental and control groups(P< 0.05).Conclusion:The whole course of pharmaceutical care intervention to the children with chronic cough and their families can improve the therapeutic effect,promote rational drug use and decrease the medication expenses.关键词
慢性咳嗽/药学服务/抗菌药物/合理用药/儿童Key words
Chronic Cough/Pharmaceutical Care/Antibiotics/Rational Use of Drugs/Children
