中国执业药师Issue(7)：31-37,7.DOI:10.3969/j.issn.1672-5433.2015.07.008
质子泵抑制剂临床应用的药学监护
Pharmaceutical Care in Clinical Use of Proton Pump Inhibitors
张石革1
作者信息
- 1. 北京大学第四临床医学院，北京积水潭医院，北京100035
- 折叠
摘要
Abstract
The development and use of proton pump inhibitors have expanded the functional mechanism of acid-inhibitory drugs. Proton pump inhibitor is highly selective to H+-K+-ATP enzyme,it can suppress the formation of gastric acid in the last step and has the inhibitory effects on basic gastric acid and stress gastric acid secretion or haemorrhage. This paper summarized the data of clinical application in hospitals in the recent four years through domestic and foreign literature review. The trend and risks of the application of proton pump inhibitors were analyzed,and the critical points in monitoring of clinical application were put forward. It was suggested that the supervision of the use of proton pump inhibitors should be strengthened,theGuidingPrinciplesforClinical ApplicationofProtonPumpInhibitorsshould be worked out and the benefit and possible risks in patients’ application should be balanced so as to promote the rational use of proton pump inhibitors.关键词
质子泵抑制剂/超适应证/应用风险/药学监护Key words
Proton Pump Inhibitors/Overindication/Application Risk/Pharmaceutical Care引用本文复制引用
张石革..质子泵抑制剂临床应用的药学监护[J].中国执业药师,2015,(7):31-37,7.
