中国中医药信息杂志Issue(10)：32-38,7.DOI:10.3969/j.issn.1005-5304.2014.10.011
中药治疗小儿支原体肺炎随机对照试验Meta分析
Meta-analysis of Randomized Controlled Trail of Traditional Chinese Medicine on Children with Mycoplasma Pneumonia
摘要
Abstract
Objective To evaluate the effectiveness and safety of TCM treatment to children with mycoplasma pneumonia. Methods RCTs of trational Chinese medicine in treating children with mycoplasma pneumonia were retrieved. CNKI, Wanfang Database and CBMdisc were searched for Chinese literature, and PubMed, EMbase and Cochrane Library were searched for foreign literature. All searching time was up to May 25, 2012. Data were picked up by two system reviewers individually and evaluation standard of Cochrane was used to evaluate the quality of selected literature. Results A total of 64 RCTs including 6289 cases of children with mycoplasma pneumonia were analyzed. In the improvement of clinical symptoms, among comparison between traditional Chinese medicine and western medicine (RR=1.10, 95%CI:-1.0--1.18) and comparison between traditional Chinese medicine plus western medicine and western medicine (RR=1.14, 95%CI:1.10-1.18), curative effects of treatment group were superior to the control group, P<0.00;For the fever clearance time, among comparison between traditional Chinese medicine and western medicine (RR=-4.26, 95%CI:-8.15--0.37), comparison between traditional Chinese medicine plus western medicine and western medicine (RR=-0.97, 95%CI:-1.27--0.66), curative effects of treatment group were superior to the western medicine group. For the time of the disappearance of cough and pulmonary rales, and the basic X-ray absorption time, curative effects of treatment group were also superior to the control group. Untoward effects in western medicine group were obvious than that of traditional Chinese medicine group. Conclusion TCM could improve and shorten the duration of symptoms of children with mycoplasma pneumonia. However, it is still necessary to be verified with more multi-center, double-blind, large sample randomized controlled trials, since the literature which have been brought into related researches were with low quality.关键词
中药/小儿支原体肺炎/Meta分析/随机对照试验Key words
traditional Chinese medicine/mycoplasma pneumonia in children/meta-analysis/RCT分类
医药卫生引用本文复制引用
王晓忠,王燕,王先敏..中药治疗小儿支原体肺炎随机对照试验Meta分析[J].中国中医药信息杂志,2014,(10):32-38,7.基金项目
新疆维吾尔自治区中医医院院级课题(zyy2011XT06) （zyy2011XT06）
