中国中医药信息杂志Issue(1)：91-94,4.DOI:10.3969/j.issn.1005-5304.2015.01.026
正交试验法优选金枣远志胶囊中贯叶金丝桃等提取工艺
Optimization of Extraction Technology of Hyperici Perforate Herba, Coptidis Rhizoma, Schisandrae Chinensis Fructus, and Ziziphi Spinosae Semen forJinzao Yuanzhi Capsule by Orthogonal Test
李磊 1李宏力 1姚宏2
作者信息
- 1. 陕西能源职业技术学院医学技术系，陕西 西安 710613
- 2. 西安万隆制药股份有限公司技术中心，陕西 西安 710119
- 折叠
摘要
Abstract
Objective To optimize the extraction conditions of Hyperici Perforate Herba, Coptidis Rhizoma, Schisandrae Chinensis Fructus, and Ziziphi Spinosae Semen forJinzao Yuanzhi Capsule.Methods Hyperin extraction rate was set as index, and HPLC was used for determination. The extraction conditions of ethanol concentration, ethanol quantity, extraction time and other factors were studied with orthogonal test and comparative test.Results Ethanol concentration and extracting times were remarkable factors in the test. The optimum extraction technology forJinzao Yuanzhi Capsule was to reflux and extract the materials with 8 times of 70% ethanol for 2 times, reflux extraction for 1.5 hours, filtration. Then 6 times of 70% ethanol was added for 1.5 hours’ reflux, filtering, and merging extracted liquid.Conclusion The optimum extraction technology is reasonable and feasible.关键词
金枣远志胶囊/正交试验/提取工艺/贯叶金丝桃/黄连/五味子/酸枣仁Key words
Jinzao Yuanzhi Capsule/orthogonal test/extraction technology/Hyperici Perforate Herba/Coptidis Rhizoma/Schisandrae Chinensis Fructus/Ziziphi Spinosae Semen分类
医药卫生引用本文复制引用
李磊,李宏力,姚宏..正交试验法优选金枣远志胶囊中贯叶金丝桃等提取工艺[J].中国中医药信息杂志,2015,(1):91-94,4.
