中国中医药信息杂志Issue(2)：42-46,5.DOI:10.3969/j.issn.1005-5304.2015.02.013
针灸治疗类风湿关节炎随机对照临床研究Meta分析
Meta-analysis on Randomized Controlled Clinical Trials of Acupuncture and Moxibustion for Rheumatoid Arthritis
摘要
Abstract
Objective To systematically assess the effectiveness and safety of acupuncture and moxibustion for treatment of rheumatoid arthritis. Methods Articles were searched from databases, i.e., CNKI, VIP, WanFang Data, CBM, Embase, and PubMed. Articles about RCT on acupuncture and moxibustion for rheumatoid arthritis and traditional medicine therapy were under meta-analysis. Results Totally 24 articles involving 2006 patients were included. The results of meta-analysis indicated that the overall effective rate of treatment in the group receiving acupuncture and moxibustion was higher than that in the drug group, with statistical significance [OR=2.73, 95%CI (2.18, 3.41), Z=8.78, P<0.000 01]. Sub-group analysis showed that:acupuncture and moxibustion showed statistical significance in decreasing serum RF levels compared with drug therapy [MD=-2.92, 95%CI (-5.60, -0.25), P<0.05]. Acupuncture and moxibustion showed statistical significance in decreasing serum ESR levels compared with drug therapy [MD=-2.99, 95%CI (-4.78, -1.21), P<0.05]. Acupuncture and moxibustion showed statistical significance in decreasing serum CPR levels compared with drug therapy [MD=-1.44, 95%CI (-2.44, -0.44), P <0.05]. Conclusion The overall effective rates of acupuncture and moxibustion for rheumatoid arthritis and the decreasing levels of RF, ESR, CRP are superior to drug therapy, but it still needs larger samples, multi-center, and high quality RCT to verify.关键词
针灸疗法/类风湿性关节炎/随机对照试验/Meta分析Key words
acupuncture-moxibustion therapy/rheumatoid arthritis/RCT/meta-analysis分类
医药卫生引用本文复制引用
张星华,朱博雯,赵彬元,秦晓光,杜小正..针灸治疗类风湿关节炎随机对照临床研究Meta分析[J].中国中医药信息杂志,2015,(2):42-46,5.基金项目
国家自然科学基金(81260558) （81260558）
