中国中医药信息杂志Issue(4)：94-97,4.DOI:10.3969/j.issn.1005-5304.2015.04.026
降脂复肝胶囊质量标准研究
Study on Quality Standard of Jiangzhi Fugan Capules
李彩东 1潘新波 1张伟 1王信1
作者信息
- 1. 兰州市第二人民医院，甘肃 兰州 730046
- 折叠
摘要
Abstract
Objective To establish the quality standard of Jiangzhi Fugan Capules. Methods TLC was used to the qualitative identification of Paeoniae Radix Rubra and Salviae Miltiorrhizae Radix et Rhizoma. The contents of Paeoniflorin and Tanshinone ⅡA were determined by HPLC. The HPLC separation was performed on Phenomenex C18 column (4.6 mm×250 mm, 5 μm), with methanol-0.1% phsophonic acid (31∶69, 75∶25) as mobile phase, and the flow rate was 1.0 mL/min. Results The results of TLC showed that relevant spots were clear without interference against the negative sample. The calibration curves for Paeoniflorin and Tanshinone ⅡA were found to be liner within the range of 0.448-4.48μg, 0.057 6-0.576μg, respectively. The correlation coefficients were 0.999 4 and 0.999 5, respectively. The average recoveries were 99.93%and 99.75%, with RSD of 1.98%(n=9) and 1.70%(n=9), respectively. Conclusion The method is accurate, reliable, stable, rapid, and reproducible, and can be used for the quality control and evaluation of Jiangzhi Fugan Capules.关键词
降脂复肝胶囊/质量标准/薄层色谱法/高效液相色谱法Key words
Jiangzhi Fugan Capules/quality standard/TLC/HPLC分类
医药卫生引用本文复制引用
李彩东,潘新波,张伟,王信..降脂复肝胶囊质量标准研究[J].中国中医药信息杂志,2015,(4):94-97,4.
