中国中医药信息杂志Issue(6):54-57,4.DOI:10.3969/j.issn.1005-5304.2015.06.016
子午流注纳甲法对急性缺血性脑卒中大鼠神经元特异性烯醇化酶、S100B蛋白的影响
Effects of Najia Method of Midday-midnight Point Selection for NSE and S100B Protein in Acute Ischemic Stroke Rats
摘要
Abstract
Objective To observe the effects of Najia method of midday-midnight point selection for acute ischemic stroke (AIS) model rats onthe contents of NSE and S100B protein in serum. Methods SPF SD male rats were chosen to establish the models by middle cerebral artery bolt method. Rats were divided into blank group, sham-operation group, model group, channel-point group, and Najia method group by random number table method. Blank group, sham-operation group, and model group were in the absence of treatment, while the channel-point group received acupuncture treatment according to differentiation syndrome. Najia method group used Najia method of midday-midnight point selection to conduct acupuncture treatment once a day. Improvement of neural function and cerebral infarction volume were observed. The contents of NSE and S100B protein in serum were detected. Results Compared with model group, neurological function score, infarct volume and infarct volume percentage, and the contents of NSE and S100B protein in serum decreased in Najia method group and channel-point group (P<0.05, P<0.01). The effects of Najia group were generally better than the channel-point group. Conclusion Najia method of midday-midnight point selection can decrease the content of NSE and S100B protein in serum of AIS model rats, so as to achieve the effects of neuroprotection and treatment.关键词
子午流注纳甲法/急性缺血性脑卒中/S100B蛋白/神经元特异性烯醇化酶/大鼠Key words
Najia method of midday-midnight point selection/acute ischemic stroke/S100B protein/NSE/rats分类
医药卫生引用本文复制引用
商俊芳,姜华,杨喜云,张武德,王金海,李志东,赵敏,鲍英存,黄春换..子午流注纳甲法对急性缺血性脑卒中大鼠神经元特异性烯醇化酶、S100B蛋白的影响[J].中国中医药信息杂志,2015,(6):54-57,4.基金项目
甘肃省中医药科学技术研究课题(GZK-2011-32) (GZK-2011-32)