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子午流注纳甲法对急性缺血性脑卒中大鼠神经元特异性烯醇化酶、S100B蛋白的影响

商俊芳 姜华 杨喜云 张武德 王金海 李志东 赵敏 鲍英存 黄春换

中国中医药信息杂志Issue(6):54-57,4.
中国中医药信息杂志Issue(6):54-57,4.DOI:10.3969/j.issn.1005-5304.2015.06.016

子午流注纳甲法对急性缺血性脑卒中大鼠神经元特异性烯醇化酶、S100B蛋白的影响

Effects of Najia Method of Midday-midnight Point Selection for NSE and S100B Protein in Acute Ischemic Stroke Rats

商俊芳 1姜华 1杨喜云 1张武德 1王金海 1李志东 1赵敏 1鲍英存 1黄春换1

作者信息

  • 1. 兰州大学第二医院,甘肃 兰州 730030
  • 折叠

摘要

Abstract

Objective To observe the effects of Najia method of midday-midnight point selection for acute ischemic stroke (AIS) model rats onthe contents of NSE and S100B protein in serum. Methods SPF SD male rats were chosen to establish the models by middle cerebral artery bolt method. Rats were divided into blank group, sham-operation group, model group, channel-point group, and Najia method group by random number table method. Blank group, sham-operation group, and model group were in the absence of treatment, while the channel-point group received acupuncture treatment according to differentiation syndrome. Najia method group used Najia method of midday-midnight point selection to conduct acupuncture treatment once a day. Improvement of neural function and cerebral infarction volume were observed. The contents of NSE and S100B protein in serum were detected. Results Compared with model group, neurological function score, infarct volume and infarct volume percentage, and the contents of NSE and S100B protein in serum decreased in Najia method group and channel-point group (P<0.05, P<0.01). The effects of Najia group were generally better than the channel-point group. Conclusion Najia method of midday-midnight point selection can decrease the content of NSE and S100B protein in serum of AIS model rats, so as to achieve the effects of neuroprotection and treatment.

关键词

子午流注纳甲法/急性缺血性脑卒中/S100B蛋白/神经元特异性烯醇化酶/大鼠

Key words

Najia method of midday-midnight point selection/acute ischemic stroke/S100B protein/NSE/rats

分类

医药卫生

引用本文复制引用

商俊芳,姜华,杨喜云,张武德,王金海,李志东,赵敏,鲍英存,黄春换..子午流注纳甲法对急性缺血性脑卒中大鼠神经元特异性烯醇化酶、S100B蛋白的影响[J].中国中医药信息杂志,2015,(6):54-57,4.

基金项目

甘肃省中医药科学技术研究课题(GZK-2011-32) (GZK-2011-32)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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