星点设计-效应面法优选治前胶囊的提取工艺OACSCDCSTPCD
Optimal Extraction of Zhiqian Capsule by Central Composite Design-Response Surface Method
目的：优选治前胶囊的提取工艺,为将该制剂开发成中药新药提供依据。方法以浸泡时间、加水量、提取时间为主要影响因素,以浸膏得率和秦皮乙素浸出量为评价指标,采用单因素试验和星点设计-效应面法优选治前胶囊的最佳提取工艺。结果优选的最佳提取工艺条件为：回流提取2次,第1次加10倍量水、提取2.5 h,第2次加8倍量水、提取2 h。结论优选的最佳提取工艺条件对秦皮乙素提取效率高,经济、合理、简单可行。
Objective To optimize the extraction technology of Zhiqian Capsule;To provide evidence for researches on preparation into new Chinese medicine. Methods The main influential factors of extraction technology included the quantity of water, extraction time and immersion time. The extraction effect was evaluated with the content of aesculetin and the extract yield as indexes. The optimal extraction technology of Zhiqian Capsule was selected by single factor expe…查看全部>>
邹龙;彭贞贞;蒋翠平;唐蓉;陈叶童;彭买姣
湖南中医药大学，湖南 长沙 410208湖南中医药大学，湖南 长沙 410208浏阳市中医院，湖南 浏阳 410300湖南中医药大学，湖南 长沙 410208湖南中医药大学，湖南 长沙 410208湖南中医药大学，湖南 长沙 410208
医药卫生
治前胶囊星点设计-效应面法提取工艺秦皮乙素
Zhiqian Capsulecentral composite design-response surface methodextraction technologyaesculetin
《中国中医药信息杂志》 2015 (6)
83-86,4
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