中国中医药信息杂志Issue(7)：89-91,92,4.DOI:10.3969/j.issn.1005-5304.2015.07.025
千金子水煎液中4种有效成分含量测定
Content Determination of Four Effective Constituents in Euphorbiae Semen Decoction
摘要
Abstract
Objective To determine the contents of four effective constituents in Euphorbiae Semen decoction;To provide evidence for Euphorbiae Semen decoction into clinical application. Methods Established quantitative analysis multi-components by single marker method was used to determine the contents of diterpenoids constituents, such as euphorbia storoid, euphorbia factor L2, and euphorbia factor L3. HPLC method was used to determine the contents of aesculetin. Results Contents of euphorbia storoid, euphorbia factor L2, and euphorbia factor L3 in smashed Euphorbiae Semen decoction were 0.015 9%, 0.005 9% and 0.024 1%, respectively. However, the contents of the above three constituents could not be detected in whole Euphorbiae Semen decoction. The content of aesculetin (0.693 6%) in smashed Euphorbiae Semen decoction was more than that in whole Euphorbiae Semen decoction (0.288 2%). Conclusion Decoction digestion effect of diterpenoids constituents in Euphorbiae Semen decoction is not good. Decocting with water is not suitable for the clinical application of Euphorbiae Semen for purgation and diuresis. Aesculetin in smashed Euphorbiae Semen decoction has good decoction digestion effect, in which clinical use for antisepsis and anti-inflammation is effective.关键词
千金子/水煎液/二萜醇酯/香豆素Key words
Euphorbiae Semen/decoction/diterpenoids/coumarin分类
医药卫生引用本文复制引用
吴瑞环,张振凌,王瑞生,沈莎莎,刘小鸣..千金子水煎液中4种有效成分含量测定[J].中国中医药信息杂志,2015,(7):89-91,92,4.基金项目
中医药行业科研专项(201107008) （201107008）
