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北京和加拿大安大略省卒中/短暂性脑缺血发作基线和住院治疗的比较--来自中国国家卒中登记和加拿大卒中登记研究的结果

刘改芬 Moira K. Kapral 王拥军 房继明 宋彦丽 潘岳松 张润华 王伊龙 赵性泉 王春雪 Frank L. Silver

中国卒中杂志Issue(9):724-730,7.
中国卒中杂志Issue(9):724-730,7.DOI:10.3969/j.issn.1673-5765.2014.09.003

北京和加拿大安大略省卒中/短暂性脑缺血发作基线和住院治疗的比较--来自中国国家卒中登记和加拿大卒中登记研究的结果

A Comparison of the Care and Outcomes of Patients with Stroke or Transient Ischemic Attack in Beijing, China and Ontario, Canada

刘改芬 1Moira K. Kapral 2王拥军 3房继明 4宋彦丽 1潘岳松 2张润华 3王伊龙 4赵性泉 1王春雪 2Frank L. Silver3

作者信息

  • 1. 100050 北京首都医科大学附属北京天坛医院神经内科
  • 2. 国家神经系统疾病临床医学研究中心
  • 3. 北京脑重大疾病研究院脑卒中研究所
  • 4. 加拿大安大略省多伦多临床科学评估研究所
  • 折叠

摘要

Abstract

Objective To compare baseline characteristics, key performance in stroke care and outcomes for stroke or transient ischemic attack (TIA) in China, Beijing with those in Ontario, Canada. <br> Methods The China National Stroke Registry (CNSR)-Beijing consecutively recruited 1775 patients with acute stroke or TIA from 11 stroke centers in Beijing between September 2007 and August 2008. We analyzed data from the CNSR-Beijing and compared the results with the data from the Ontario Stroke Registry, which contained 3551 stroke or TIA patients from 11 stroke&nbsp;centers in Ontario, Canada between April 2007 and March 2008. <br> Results Patients in Beijing were younger than those in Ontario (mean±SD of age in years:64.5±12.9 vs 70.2±15.3, P<0.001) and were more likely to be male (64.8%vs 51.6%, P<0.001). Compared with patients in Ontario, those in Beijing were less likely to present to the Emergency Department (ED) via ambulance (33.5%vs 78.4%, P<0.001) and to arrive to the ED within 2.5 hours of stroke onset (21.0%vs 42.4%, P<0.001). Patients in Beijing were less likely than those in Ontario to undergo neuroimaging (93.9%vs 99.2%, P<0.001) or to be admitted to a stroke unit (23%vs 64.7%, P<0.001). Among patients with ischemic stroke, those in Beijing were less likely to receive thrombolysis than those in Ontario (8.1%vs 17.4%, P<0.001), while those with atrial ifbrillation were similar to be prescribed oral anticoagulants at discharge (75.9%vs 75.5%, P=0.945). A similar proportion in Beijing and Ontario were prescribed antithrombotics at discharge (77.0%vs 77.9%, P=0.544) in ischemic stroke patients. New strokes during hospitalization were significantly lower in Beijing than in Ontario (3.4%vs 5.1%, P=0.006), whereas pneumonia after stroke was more frequent (12.5%vs 7.6%, P<0.001). Case-fatality rates were lower in Beijing than those in Ontario in-hospital (7.7%vs 14.7%), at 7 days (5.7%vs 9.3%), and at 30 days (7.9%vs 15.9%) after stroke (P<0.001 for all comparisons). <br> Conclusion There are substantial differences in demographics, hospital care and outcomes after stroke between Beijing and Ontario. Awareness of these differences may be helpful in improving the quality of hospital care, stroke control and prevention strategies in China.

关键词

卒中/卒中治疗/结局事件

Key words

Stroke/Stroke care/Outcome

引用本文复制引用

刘改芬,Moira K. Kapral,王拥军,房继明,宋彦丽,潘岳松,张润华,王伊龙,赵性泉,王春雪,Frank L. Silver..北京和加拿大安大略省卒中/短暂性脑缺血发作基线和住院治疗的比较--来自中国国家卒中登记和加拿大卒中登记研究的结果[J].中国卒中杂志,2014,(9):724-730,7.

基金项目

十一五国家科技支撑计划(2006BAI01A11)国家科技支撑计划项目(2013BAI09B03)北京脑重大疾病研究院项目(BIBD-PXM2013_014226_07_000084)首都卫生发展科研专项项目(首发2011-2004-05)北京市科技计划重大项目 ()

中国卒中杂志

OACSTPCD

1673-5765

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