中国卒中杂志Issue(3)：218-224,7.DOI:10.3969/j.issn.1673-5765.2015.03.005
血浆甘油三酯水平与缺血性卒中出院结局关系研究
Relationship between the Triglyceride Levels and the Outcome of Ischemic Stroke
摘要
Abstract
Objective To assess the relationship between admission triglyceride levels and discharged poor outcome in patients with acute ischemic stroke. <br> Methods We performed a retrospective cohort study of 3351 patients with acute ischemic stroke, who came from the People's Hospital of Inner Mongolia Xinganmeng from June 1, 2009 to May 31, 2012. Poor outcome was deifned as discharged modiifed Rankin Scale (mRS) score 3. Compare the baseline data between poor outcome group and good outcome group. Triglyceride at admission was divided into 4 levels using the quartile method. Non-conditional Logistic regression analysis was used to assess the relationship between admission triglyceride levels and discharged poor outcome in patients with acute ischemic stroke, by calculating the odds ratio (OR) and 95%conifdence interval (CI). <br> Results A total of 341 people in the study of poor outcomes, the incidence was 10.2%. Univariate non-conditional Logistic regression analysis showed that the incidence of poor outcomes in the 1, 2, 3 percentile group (TG was 1.06 mmol/L, 1.06~1.46 mmol/L, 1.46~2.12 mmol/L) was significantly different with the highest relative percentile group (TG>2.12 mmol/L) (P<0.05). After adjusting for age, length of hospital stay, time of onset to hospitalization, ifrst ischemic stroke, smoking, drinking, history of heart disease, ifbrillation, hypertension, hyperglycemia, heart rate and triglyceride levels, compared with the highest relative percentile group, the incidence of poor outcomes in the 3 percentile group was not significantly different (P=0.0758), while the incidence of poor outcomes in the 1, 2 quartile group was signiifcantly different (P<0.0001), the values of OR (95%CI) were 1.883(1.307~2.714) and 2.063(1.436~2.963). <br> Conclusion Lower triglyceride levels at admission may independently increase the risk of discharged poor outcomes in patients with acute ischemic stroke.关键词
急性,缺血性卒中/甘油三酯/出院/结局不良Key words
Acute, Ischemic stroke/Triglycerides/Discharge/Poor outcome引用本文复制引用
黄萍,李志杰,吕利英,马龙,杨丽荣,国钰梅,白文婷,包成月,佟伟军..血浆甘油三酯水平与缺血性卒中出院结局关系研究[J].中国卒中杂志,2015,(3):218-224,7.基金项目
国家自然科学基金资助项目 （）
