中国卒中杂志Issue(4):331-335,5.DOI:10.3969/j.issn.1673-5765.2015.04.010
MiRNA与血小板活性的研究进展:一个新的评估抗血小板治疗效果的潜在生物标志物
Advances in Correlation between miRNA and Platelet Activity:a Novel and Potential Biomarker to Evaluate the Efficacy of Anti-platelet Therapy
摘要
Abstract
MicroRNA (miRNA) is a non-coding small RNA molecule, participating in regulating biologic activities, with a large quantity. MiRNAs have their specific expression in different processes related to platelet formation, mRNA regulation, protein synthesis and platelet activation. For instance, miRNA participates in regulating the biogenesis and differentiation of megakaryocytes and the pathway of platelet activation. Scientists pay a lot of efforts to ifgure out the relationship between miRNA and platelet reactivity, which points out a new possibility to evaluate the efifcacy of anti-platelet therapy by using miRNA as a novel biomarker. This article is trying to review the studies about the relevance between miRNA and platelet reactivity.关键词
微RNA/血小板/生物标志物Key words
MicroRNA/Platelet/Biomaker引用本文复制引用
林泽明,刘新通..MiRNA与血小板活性的研究进展:一个新的评估抗血小板治疗效果的潜在生物标志物[J].中国卒中杂志,2015,(4):331-335,5.基金项目
广东省科学技术厅资助项目 ()