中华耳科学杂志Issue(2)：203-206,4.DOI:10.3969/j.issn.1672-2922.2014.02.04
耳鸣患者静息态fMRI的局部区域一致性研究
Resting-State fMRI Regional Homogeneity in Tinnitus Patients
摘要
Abstract
[Objective]To study central functional network connections and their alterations in tinnitus patients using fMRI. Meth-ods fMRI was performed in 18 tinnitus patients and 20 controls. Regional consistency (regional homogeneity or ReHo value) and functional network connection alterations were compared between the tinnitus patients and controls. Results Tinnitus pa-tients showed increased ReHo values in gyrus frontalis inferior and decreased ReHo values in anterior lobe of cerebellum in comparison with the controls. The regions with decreased ReHo values were bilateral inferior frontal gyrus, middle frontal gy-rus and anterior cingulate. Conclusions Abnormal fMRI changes in auditory cortex and non-auditory cortex are present in tin-nitus patients. The severity of tinnitus is linearly correlated to the changes in some brain regions. fMRI may be useful in evalu-ating tinnitus.关键词
耳鸣严重程度/THI/fMRI/ReHo值/功能连接Key words
Severity of tinnitus/THI/fMRI/Reho value/Functional connections分类
医药卫生引用本文复制引用
杨海弟,郑亿庆,区永康,黄夏茵..耳鸣患者静息态fMRI的局部区域一致性研究[J].中华耳科学杂志,2014,(2):203-206,4.基金项目
国家自然科学基金（81170921)；广东省自然科学基金（S2011010004576) （）
