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刺激声间隔觉察阈测试在听神经病患者诊断中的临床应用

于澜 冀飞 史伟 王洪阳 尹自芳 王大勇 王秋菊

中华耳科学杂志Issue(2):216-219,4.
中华耳科学杂志Issue(2):216-219,4.DOI:10.3969/j.issn.1672-2922.2014.02.07

刺激声间隔觉察阈测试在听神经病患者诊断中的临床应用

Clinical Application of Random Gap Detection Test

于澜 1冀飞 1史伟 1王洪阳 1尹自芳 1王大勇 1王秋菊1

作者信息

  • 1. 解放军总医院耳鼻咽喉头颈外科-耳内科 解放军耳鼻咽喉研究所 北京100853
  • 折叠

摘要

Abstract

Objective To establish a method of Random Gap Detection Test (RGDT) and to compare the Gaps-in-Noise (GIN) threshold and perceived auditory threshold of interval among normal hearing young people, patients with sensorineural hearing loss and patients with auditory neuropathy (AN) patients. Methods The interval between testing sound signals was ma-nipulated to test auditory temporal integration capability against a background noise. An adaptive approach was used, i.e., diffi-culties increased upon two consecutive correct answers and decreased (increasing interval) upon a wrong answer. The GIN test was applied to 60 normal hearing ears, 25 ears with sensorineural hearing loss and 20 ears with auditory neuropathy. One-way ANOVA was used for comparison among the normal hearing, sensorineural hearing loss and auditory neuropathy groups. Re-sults The GIN threshold of the auditory neuropathy group (29.59 ± 19.27 ms) was longer than the normal hearing (3.34 ± 1.24 ms) and sensorineural hearing loss (5.34±2.78 ms) groups. Within the normal hearing group, the GIN thresholds of the females (2.95 ± 0.86 ms) and males (3.10 ± 1.15 ms) showed no significant gender difference (P=0.683>0.05, F=0.138). The binaural GIN threshold was 3.02 ± 1.00 ms. The left ear GIN threshold (3.63 ± 1.39 ms) was not significantly different from that of the right ear (3.38±1.25 ms) (P=0.162>0.05, F=1.857). Conclusions RGDT test is a useful clinical tool in assessment of auditory temporal resolution. It is highly feasible and has profound values in clinical application, especially for patients with AN, facili-tating differential diagnosis. It can also be used as a complementary tool to verify the result of speech audiometry.

关键词

间隔觉察测试/间隔觉察阈/时间分辨率/听神经病

Key words

Random Gap Detection Test/Gaps-in-Noise/Temporal Resolution/Auditory Neuropathy

分类

生物科学

引用本文复制引用

于澜,冀飞,史伟,王洪阳,尹自芳,王大勇,王秋菊..刺激声间隔觉察阈测试在听神经病患者诊断中的临床应用[J].中华耳科学杂志,2014,(2):216-219,4.

基金项目

本研究由国家重大科学研究计划项目(2014CB943001),国家自然基金重大国际合作项目(81120108009)及全军“十二五”重点项目(BWS11J026)联合资助 (81120108009)

中华耳科学杂志

OA北大核心CSCDCSTPCD

1672-2922

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