中华耳科学杂志Issue(2)：224-227,4.DOI:10.3969/j.issn.1672-2922.2014.02.09
单侧感音神经性耳聋患者低频振幅功能磁共振研究
Resting-state Functional MR Study in Unilateral Sensorineural Hearing Loss by Amplitude of Low-frequency Fluctuation
摘要
Abstract
Objective To investigate the change of amplitude of low-frequency fluctuation (ALFF) in resting-state func-tional magnetic resonance imaging (fMRI) in patients with long-term right side sensorineural hearing loss (SNHL). Methods Resting-state fMRI data were collected from 20 patients with long-term right side sensorineural hearing loss and 20 normal subjects. Using these data, the ALFF were mapped following post-BOLD processing and compared between the SNHL and nor-mal groups. Results In the SNHL group, the ALFF showed a significant increase in bilateral superior and middle temporal gy-ri, insular lobes, uncinate gyri, right parahippocampal gyri and anterior lobe of cerebellum, and a decrease in the posterior part of right middle temporal gyrus. Conclusion The activation changes in relevant brain regions of patients with right side SNHL indicate the potential mechanisms of the brain function remodeling.关键词
磁共振成像/听觉皮层/感音神经性聋Key words
Magnetic resonance imaging/Auditory cortex/Sensorineural hearing loss分类
医药卫生引用本文复制引用
冯源,陈宇辰,刘斌,张玲玲,杨明,黄志纯..单侧感音神经性耳聋患者低频振幅功能磁共振研究[J].中华耳科学杂志,2014,(2):224-227,4.基金项目
国家自然科学基金面上项目 （）
