中华耳科学杂志Issue(2)：349-354,6.DOI:10.3969/j.issn.1672-2922.2015.02.038
AP-2蛋白调控网格蛋白介导突触囊泡胞吞的研究进展
The Progress of AP-2 Protein Regulating Clathrin Mediated Endocytosis
摘要
Abstract
Neural transmission is dependent on the release of neurotransmitter. Synaptic vesicle recycling is the basis of neurotransmitter release. Clathrin-mediated endocytosis plays a key role in the synaptic vesicle reformation. AP-2 is a key protein in different periods of endocytosis, which can bind other protein molecules to regulate the vesicle recycling from the as⁃pects of structure and dynamics. This review summarizes the molecular structure and characteristic of AP-2 and discusses the relationship between clathrin-mediated endocytosis and hearing.关键词
网格蛋白/衔接蛋白/胞吞/突触囊泡/内毛细胞Key words
Clathrin/Adaptin/Endocytosis/Ssynaptic vesicle/Inner hair cell分类
医药卫生引用本文复制引用
顾翔,袁伟..AP-2蛋白调控网格蛋白介导突触囊泡胞吞的研究进展[J].中华耳科学杂志,2015,(2):349-354,6.基金项目
国家自然科学基金资助项目（81470694，30973301，81271080），重庆市自然基金资助项目 （）
