中华临床免疫和变态反应杂志Issue(3)：254-258,5.DOI:10.3969/j.issn.1673-8705.2014.03.016
多发性大动脉炎免疫发病机制
Immunopathogenesis of Takyasu’s Arteritis
张倩茹 1郭娟 1周炜1
作者信息
- 1. 北京大学第一医院风湿免疫科，北京 100034
- 折叠
摘要
Abstract
Takayasu’s arteritis is a chronic inflammatory disease that mainly affects the aorta and its major branches,and is characterized by the presences of immune cells infiltration in all layers of vascular wall. The etiology of this disease is still unknown.Many factors may be involved in its pathogenesis,including infection, genetics and immunity. We reviewed the studies about the mechanisms underlying the immunopathogenesis of TA.Cell-mediated autoimmunity has been strongly implicated in the pathogenesis of TA,however,the role of humoral immunity remains to be elucidated.关键词
大动脉炎/发病机制/细胞免疫/体液免疫Key words
Takayasu’s arteritis/pathogenesis/cellular immunity/humoral immunity分类
医药卫生引用本文复制引用
张倩茹,郭娟,周炜..多发性大动脉炎免疫发病机制[J].中华临床免疫和变态反应杂志,2014,(3):254-258,5.
