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首页|期刊导航|中华脑科疾病与康复杂志(电子版)|常用新型抗癫痫药物对癫痫患儿认知功能的影响

常用新型抗癫痫药物对癫痫患儿认知功能的影响

石景鹤 王家勤 陈国洪

中华脑科疾病与康复杂志(电子版)Issue(5):40-43,4.
中华脑科疾病与康复杂志(电子版)Issue(5):40-43,4.DOI:10.3877/cma.j.issn.2095-123X.2014.05.009

常用新型抗癫痫药物对癫痫患儿认知功能的影响

Effects of commonly used new antiepileptic drugs on cognitive function in children with epilepsy

石景鹤 1王家勤 2陈国洪1

作者信息

  • 1. 450053 郑州市儿童医院神经内科
  • 2. 新乡医学院第三附属医院小儿科
  • 折叠

摘要

Abstract

Epilepsy is a chronic disease of the nervous system which is commonly contracted by children.The cognitive abilities of these affected children are mostly in an average level ,but still lower as a whole than those of the normal children .The cognitive impairment caused by epilepsy is mainly reflected in the children′s decreasing ability of integrating the external information .The extent of the damage caused by this impairment to the integrating ability can be decided by the epilepsy′s seizure type ,age of onset ,affection process,seizure frequency,disease duration,lesion focus,basic diseases/causes that may lead to epilepsy, social psychology,and so on.For a long time,the most important objective of epilepsy treatments has been to take control of epilepsy seizures .A great deal of current experiments and researches has demonstrated that the theory of newly-invented anti-epilepsy medicines is to contain epilepsy seizures through neurotransmission ,ion channels,second messenger and other links .In this way,the cognitive impairment is relieved and the patient′s life quality improved .However , one disadvantage of this treatment is its harmfulness to the children′s cognitive functions in some ways.Antiepileptic drugs through the neurotransmitter ,ion channels,the second messenger ,and other links to adjust control seizures .Thus reduce cognitive impairment of epilepsy , improve the quality of life of patients ,but also affect children′s cognitive function in some ways .

关键词

癫痫/认知障碍/抗惊厥药/影响

Key words

Epilepsy/Cognition disorders/Anticonvulsants/Impact

引用本文复制引用

石景鹤,王家勤,陈国洪..常用新型抗癫痫药物对癫痫患儿认知功能的影响[J].中华脑科疾病与康复杂志(电子版),2014,(5):40-43,4.

中华脑科疾病与康复杂志(电子版)

2095-123X

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