中华脑科疾病与康复杂志（电子版）Issue(6)：19-25,7.DOI:10.3877/cma.j.issn.2095-123X.2014.06.004
磁共振弥散加权成像与卒中后抑郁的相关研究
Related research on magnetic resonance imaging diffusion weighted imaging and post-stroke depression
摘要
Abstract
Objective To analyze the diffusion weighted imaging ( DWI) and the data of follow-up of acute ischemic stroke patients ,according to related risk factors and the severity of stroke to try to explore the relationship of the stroke lesion on the diffusion weighted imaging and post-stroke depression (PSD),which could provide help in the prevention of PSD and improve the quality of life of stroke patients . Methods Seventy patients who recepted treatment from the Third Department of Neurology in the First Affiliated Hospital of Harbin Medical University during July 2013 to October 2013 who were accord with our enter criterion were chosen in our study ,and information such as gender ,age,history of hypertension ,diabetes mellitus,history of coronary heart disease,smoking history,drinking history,level of education,social support and other information were collected .All these patients were given proper treatment , such as improving circulation,trophic nerve and controling risk factors .The patients finished DWI as soon as possible .They would be asked to continue their treatment for secondary prevention and cooperate to complete the collection of clinical data and follow-up ( from 2 weeks of admission , 1 month, 3 months ) , the relationships of the incidence of post-stroke depression and the new location of the lesion on weighted magnetic resonance imaging were observed and compared .Results The comparison of the incidence of PSD of acute ischemic stroke patients whose responsibility lesions was showed on DWI lesions in 3 months:multiple cerebral infarction( 75.00%) >frontal lobe infarction ( 50.00%) >limbic system infarction ( 21.43%) >basal ganglia infarction(12.50%),and the incidence of PSD had significant difference (P<0.05);On 2 weeks:multiple cerebral infarction ( 50.00%) >frontal lobe infarction ( 18.75%) >limbic system infarction (7.14%)>basal ganglia infarction(0),and the incidence of PSD had significant difference (P<0.05). Patients who were showed multiple cerebral infarction on DWI , the comparison of PSD had significant difference(P<0.05).Conclusion The incidence of PSD on 2 weeks and 3 months and is relevant to new lesions on DWI , and the incidence of PSD in multiple cerebral infarction is higher than the other system infarction and relevant with the follow-up time.There is no relevance between the incidence of PSD and deferent follow-up times on these who are showed single infarction (frontal lobe,limbic system,basal ganglia) on DWI.DWI can prompt PSD in someways .关键词
卒中/脑缺血/磁共振成像,弥散/卒中后抑郁Key words
Stroke/Brain ischemia/Diffusion magnetic resonance imaging/Post-stroke depression引用本文复制引用
王晓羽,王春燕,赵越,潘永惠..磁共振弥散加权成像与卒中后抑郁的相关研究[J].中华脑科疾病与康复杂志（电子版）,2014,(6):19-25,7.基金项目
黑龙江省自然科学基金项目（ H201346）；黑龙江省教育厅科学技术研究基金资助项目（11551218）；哈尔滨市科技创新人才研究专项资金项目 （）
