中华脑科疾病与康复杂志（电子版）Issue(6)：31-35,5.DOI:10.3877/cma.j.issn.2095-123X.2014.06.006
神经内镜与显微镜经单鼻孔蝶窦入路切除垂体腺瘤疗效比较
Comparison of curative effect of resection of pituitary adenoma by endoscope and microscope single nostril transsphenoidal approach
摘要
Abstract
Objective To compare the curative effect of resection of pituitary adenoma by endoscope and microscope single nostril transsphenoidal approach.Me thods From July 2007 to July 2008 ,40 cases of endoscopic ( endoscopic group ) and 24 cases of microscope ( microscopy group ) by transsphenoidal removal of pituitary adenomas patients with clinical data were retrospectively analyzed ,the operation curative effect were compared.t test, rank sum test or χ2 were used to compare the differences between the two groups . Results Total resection rate in endoscopic group was 92.5%,while in microscopy group total was 83.3%, there was no statistical difference between the two groups (χ2 =0.524 , P =0.469 ) .Operation time in endoscopy group was 2.1 ( 0.50 ) h, while in microscopy group was 2.6 ( 1.15 ) h, there was no statistical difference between the two groups (Z=-1.848,P=0.065).The amount of bleeding in endoscopy group [20.0(5.00)ml]was less than that in microscopy group [25.5(12.25)ml,Z=-3.757,P=0.000];Hospitalization time in endoscopy group [(8.75 ±2.753) d] was significantly shorter than the microscope group [(15.13 ±3.069)d,t =-8.591,P=0.000].In endoscopic group,there were 2 cases of diabetes insipidus,electrolyte disorder in 4 cases,in microscopy group,there were 2 cases of diabetes insipidus, leakage of cerebrospinal fluid in 2 cases,fever in 1 cases,electrolyte disorders in 4 cases,nasal septal defect in 6 cases.Except the nasal septum defect had significant difference between the two groups (χ2 =8.288,P=0.004 ) ,there was no significant difference in other complication rates ( P>0.05 ) .Conclusion Endoscope and microscope place an order nostril transsphenoidal approach for pituitary adenoma resection with curative effect and safety.The endoscopic treatment for bleeding , hospitalization time, complications have more advantages ,and it will be the development direction operation of the neurosurgery in the future .关键词
内窥镜检查/显微镜检查/垂体腺瘤Key words
Endoscopy/Microscopy/Pituitay adenoma引用本文复制引用
刘宇利,郑勇,成振林,王继超,吴永刚,张诚,高峰..神经内镜与显微镜经单鼻孔蝶窦入路切除垂体腺瘤疗效比较[J].中华脑科疾病与康复杂志（电子版）,2014,(6):31-35,5.基金项目
吴阶平医学基金会临床科研专项资助基金 （）
