神经药理学报Issue(5)：1-4,4.
冠心病相关抑郁症的中西医结合治疗研究
Coronary Heart Disease-related Depression Integrative Medicine Research
摘要
Abstract
Objective:To assess the clinical efficacy of Tongxinjieyufang in treating coronary heart disease-related depression. Methods:70 coronary heart disease patients with comorbid depression were randomly assigned into two groups:35 patients for traditional Chinese medicine group treated with Tongxijieyufang and 35 patients for control group treated with fluoxetine. Both groups were maintained with their regular coronary heart disease pharmacotherapies. The study course was induced 8 weeks and the patient symptoms, electrocardiographic changes, hamilton depression rating scale (HAMD), self-rating depression scale score (SDS) and traditional Chinese medicine (TCM) single symptom score were assessed before and after treatment. Results: Both groups demonstrated significant improvements (P<0.05) on measures of angina pectoris, HAMD and SDS scores, the efficacy of TCM symptom score individual aspects, the Tongxinjieyufang group had better improvements than fluoxetine group. Conclusion: Both treatments improved depressive symptoms, with Tongxinjieyufang group showing a bigger improvement. Tongxinjieyufang improved not only the symptoms of angina pectoris, but also depression scores, reduced the impact of depression on coronary heart disease, suggesting that traditional Chinese medicine has obvious advantage in the treatment of coronary heart disease-related depression.关键词
冠心病相关抑郁症/益气活血解郁法/氟西汀Key words
coronary heart disease-related depression/yiqihuoxue stagnation law/fluoxetine分类
医药卫生引用本文复制引用
秦合伟,刘萍..冠心病相关抑郁症的中西医结合治疗研究[J].神经药理学报,2012,(5):1-4,4.基金项目
上海市高级中西医结合人才培养项目 （）
