神经药理学报Issue(5):51-56,6.
沉默突触的激活机制及其功能意义
Silent Synapse:A Review
摘要
Abstract
Silent synapse is defined as a synapse that is incapable of exerting neurotransmission in physiological conditions but could be activated under certain conditions. The change of function and structure of synapses are defined as plasticity of synapse, and this property of synapses is related to restoration of the neurons and memory improvement. It is essential to understand the mechanisms of formation, function and activation of silent synapse.关键词
沉默突触/谷氨酸/长时程增强/神经可塑性/N-甲基-D-天冬氨酸(NMDA)受体/α-氨基-3-羟基-5-甲基-4-异恶唑丙酸(AMPA)受体Key words
silent synapse/glutamic acid/long-term potentiation/neuronal plasticity/N-methyl-D-aspartate (NMDA) receptor/α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor分类
医药卫生引用本文复制引用
蔡靓,苏朝芬,罗焕敏..沉默突触的激活机制及其功能意义[J].神经药理学报,2012,(5):51-56,6.基金项目
国家自然科学基金项目(No.81173037),国家重点基础研究发展计划(973计划)项目(No.2011CB707500),广东省科技计划项目 ()