神经药理学报Issue(1):48-64,17.
咪唑啉I2受体神经药理学研究进展
The Neuropharmacology of Imidazoline-I2 Receptors
摘要
Abstract
Imidazoline-I2 receptor is a group of non-G protein-coupled receptors (GPCR). Its physiological function and clinical significance remains elusive. Accumulating evidence has implicated the imidazoline-I2 receptors in a wide range of behavioral effects, including analgesia, antidepressant-like effects, modulation ofμopioid receptors and neuroprotection. Here, we provided an updated overview of its location, molecular structure, signal transduction, endogenous ligands, synthetic ligands and related neuropharmacological effects.关键词
咪唑啉I2受体/配体/神经药理学Key words
imidazoline-I2 receptor/ligand/neuropharmacology引用本文复制引用
邱艳艳,李俊旭,何小华..咪唑啉I2受体神经药理学研究进展[J].神经药理学报,2013,(1):48-64,17.基金项目
美国国立卫生研究院NIH ()