神经药理学报Issue(4)：47-57,11.
快速眼球运动睡眠剥夺对记忆和突触可塑性的影响及其分子机制的研究进展
Review on the Impact of Rapid Eye Movement Sleep Deprivation on Synaptic Plasticity and its Molecular Mechanisms
摘要
Abstract
Insufficient sleep is an increasing serious problem to men and women in fast-paced modern society. Long-term insufficient sleep can lead to cognitive dysfunction. It has been widely recognized that sleep deprivation can affect the learning and memory ability of experimental animals. In this review, we summarized the new developments regarding the impact of rapid eye movement sleep deprivation on synaptic plasticity and its molecular mechanisms in recent years, which we hope can provide some basis for relevant studies of therapeutic targets and treatment drugs in future studies.关键词
睡眠剥夺/记忆/突触可塑性/NMDA受体/腺苷/cAMP/PKA/CREB信号通路/MAPK/ERK信号通路Key words
sleep deprivation/memory/synaptic plasticity/NMDA receptor/adenosine/cAMP/PKA/CREB signal path/MAPK/ERK signal path分类
医药卫生引用本文复制引用
李炜,李婷婷,齐赛卿,张癸荣..快速眼球运动睡眠剥夺对记忆和突触可塑性的影响及其分子机制的研究进展[J].神经药理学报,2013,(4):47-57,11.基金项目
国家自然科学基金项目（No.81202192），河北省卫生厅项目（No. 20130037），河北省教育厅项目 （）
