浙江医学Issue(9):770-771,784,3.
带状疱疹后遗神经痛患者糖代谢异常情况的研究
Abnormal glucose metabolism in patients with postherpetic neuralgia
摘要
Abstract
Objective To analyze glucose metabolism in patients with postherpetic neuralgia (PHN). Methods 31 pa-tients with thoracic PHN (PHN group) and 62 healthy subjects (control group) were enrolled in the study. The anamnestic data (dietary habits, life style, drug use), demographic information (age, sex), body mass index, waist circumference and serum HbA1c were documented in both groups;the glucose and insulin levels at fasting and after 2h- OGTT were measured and skin thoracic biopsy was performed for smal fiber neuropathy in PHN groups. Results Medical records and demographic information were not significantly different between two groups(P>0.05). 2h- OGTT showed that the prevalence of glucose metabolism abnormal-ity was significantly higher in PHN group than that in control group, especial y for impaired glucose tolerance (IGT) (P<0.05). Skin biopsy detected smal fibers neuropathy in 14 out of 31 patients with PHN;PHN patients with abnormal glucose metabolism, es-pecial y IGT had higher prevalence of smal fibers neuropathy (P<0.05). Conclusion Patients with PHN have higher prevalence of abnormal glucose metabolism and PHN Patients with abnormal glucose metabolism have higher prevalence of smal fibers neuropathy.关键词
带状疱疹后遗神经痛/糖代谢异常/小纤维神经病Key words
Postherpetic neuralgia/Abnormal glucose metabolism/Smal fibers neuropathy引用本文复制引用
吴鹤芬,刘鹤,刘洋..带状疱疹后遗神经痛患者糖代谢异常情况的研究[J].浙江医学,2014,(9):770-771,784,3.