摘要
Abstract
Objective To investigate serum retinol binding protein (RBP) levels in renal diseases. Methods Serum RBP, creatinine,urea,albumin, parathyroid hormone(PTH),β2 microglobulin were determined in 167 patients with renal disease. Results The serum creatinine, urea, PTH, RBP and β2 microglobulin levels were increased with the decreasing glomerular filtration rate (GFR). When GFR was lower than 60 ml/ (min·1.73m2), there were significant differences in serum RBP, creatinine and β2 mi-croglobulin levels between patients and controls. RBP levels were positively correlated with creatinine, urea, PTH and β2 mi-croglobulin(P<0.05);negatively correlated with endogenous creatinine clearance rate (Ccr) (P<0.05). Conclusion Serum RBP levels are increased in renal diseases, which may indicate the degree of severity of renal impairment in patients with nephropathy.关键词
视黄醇结合蛋白/肾脏疾病/早期诊断Key words
Retinol binding protein/Renal diseases/Early diagnose
