浙江医学Issue(12)：1091-1092,1124,3.
不同麻醉方式对老年人全髋置换术后下呼吸道感染的影响
Impact of different anesthesia approaches on postoperative lower respiratory tract infection in elderly patients undergoing total hip arthroplasty
李清平 1吴红利1
作者信息
- 1. 316000 舟山市中医骨伤联合医院麻醉科
- 折叠
摘要
Abstract
Objective To investigate the effects of different anesthesia approached on postoperative lower respiratory tract infection in elderly patients undergoing total hip arthroplasty. Methods Fifty six patients aged 65 years who underwent total hip arthroplasty we re randomly assigned to receive intratracheal general anesthesia (control group, n=34) or general anesthesia combined with epidural block(combination group, n=22). The venous blood samples were taken before (T1) operation, during oper-ation(T2) and immediately (T3), 24h (T4) and 7d (T5) after operation. The subset of T lymphocytes (CD3+, CD4+, CD8+) were measured with flow cytometry, and the incidence of postoperative lower respiratory tract infections within 7 days was documented. Results There was no significant difference in subsets of T lymphocyte (CD3+, CD4+, CD8+) at T1 between two groups. The serum levels of CD3+[(60.7±3.7)%, (58.9±3.1)%], CD4+[(37.5±5.0)%, (36.3±3.8)%] T lymphocyte were higher in combination group than those in control group at T2 and T3(P<0.01);however, there was no significant difference at T4 and T5 between two groups(P>0.05). Two pa-tients in control group were complicated with lower respiratory tract infections within 7 d after operation with a infection rate of 5.88%, while no patients had infection in combination group. Conclusion The general anesthesia combined with epidural block may improve the perioperative immune status with a reduced risk of postoperative lower respiratory tracts infections.关键词
不同麻醉方式/术后下呼吸道感染/全髋置换术Key words
Anesthesia approach/Postoperative lower respiratory tracts infection/Total hip arthroplasty引用本文复制引用
李清平,吴红利..不同麻醉方式对老年人全髋置换术后下呼吸道感染的影响[J].浙江医学,2014,(12):1091-1092,1124,3.
