浙江医学Issue(13)：1153-1155,3.
转氨酶水平在闭合性肝损伤患者中的意义
Liver transaminase levels in patients with blunt abdominal trauma
摘要
Abstract
Objective To investigate liver transaminase levels in patients with blunt abdominal trauma. Methods The clinical data of 163 patients with blunt abdominal injury admitted between January 2011 and January 2013 were retrospectively analyzed. The grading of the hepatic trauma was verified using CT scans or surgical findings. The patients were managed with surgical or non- surgical approaches. Results There were 79 patients with hepatic trauma and 84 patients without hepatic trau-ma. The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in patients with hepatic trauma were sig-nificantly higher than those in patients without hepatic trauma [(358.21±77.48)U/L vs (930.85±14.58)U/L, P=0.000;and (416.32± 88.00)U/L vs (33.50±8.12)U/L, P=0.000]. In receiver operating characteristic (ROC) curve assessment, the optimum thresholds of ALT and AST in diagnosis of hepatic trauma were 53.00U/L and 67.50 U/L, respectively. The ALT and AST levels in patients with major hepatic trauma (gradesⅢ- Ⅵ, n=55) were significantly higher than those with minor hepatic trauma (grades I- Ⅱ, n=24) [(431.91±104.46)U/L vs (189.33±57.71)U/L, P=0.004 and (488.47±120.18)U/L vs (251.00±69.35)U/L, P=0.014]. There were no significant differences in ALT and AST levels between operation group and non- operation group [(448.96 ±140.45)U/L vs (311.10±93.03)U/L, P=0.098 and (510.41±166.46)U/L vs (367.48±103.40)U/L, P=0.132]. Conclusion The measurement of liver transaminase levels in patients with blunt abdominal trauma can differentiate patients with hepatic trauma from those without hep-atic trauma, and also differentiate major hepatic trauma from minor hepatic trauma.关键词
转氨酶/闭合性肝损伤/闭合性腹部损伤Key words
Transaminase/Blunt hepatic trauma/Blunt abdominal injury引用本文复制引用
陈祝华,沈国,陈刚红,朱铁明,陈铁炯..转氨酶水平在闭合性肝损伤患者中的意义[J].浙江医学,2014,(13):1153-1155,3.基金项目
2012绍兴市科技计划项目 （）
