浙江医学Issue(16)：1395-1397,3.
急性冠状动脉综合征患者BNP水平及其影响因素分析
BNP levels and its influencing factors in patients with acute coronary syndrome
蔡燕军 1项美香2
作者信息
- 1. 宁波市镇海龙赛医院
- 2. 310009 杭州，浙江大学医学院附属第二医院心内科
- 折叠
摘要
Abstract
Objective To investigate the B- type natriuretic peptide(BNP) level and its influence factors in patients with a-cute coronary syndrome(ACS). Methods One hundred patients with coronary heart disease patients admitted from June 2012 to January 2013 were enrol ed in the study, including 20 cases of stable angina (STEMI), 35 cases of unstable angina (UA) and 45 cases of non- ST- segment elevation myocardial infarction (NSTEMI). The BNP, C- reactive protein (CRP) levels were tested, the left ventricular ejection fraction(LVEF) was examined and the extent of coronary stenosis(Gensini score) was calculated. The influ-ence factors of BNP level was analyzed with Logistic regression. Results The BNP and CRP and Gensini score in AMI group were higher than those in UA and STEMI groups (al P<0.05);those in UA group were higher than those in STEMI group (al P<0.05). LVEF in AMI, UA groups was lower than that in STEMI group(P<0.05), while there was no significant difference between A-MI and UA groups (P>0.05). The incidence of adverse cardiac events in patients with BNP >250ng/L was higher than that in those with BNP≤250 ng/L (P<0.05). Logistic regression analysis found that BNP was positively correlated with CRP and Gensini score, and negatively correlated with LVEF (P<0.05 or 0.05). Conclusion The levels of BNP can be used as an indicator for de-gree of coronary artery lesions and predict the disease outcome in patients with acute coronary artery syndrome.关键词
急性冠状动脉综合征/B型钠尿肽/Gensini积分Key words
Acute coronary artery syndrome/B- type natriuretic peptide/Gensini score引用本文复制引用
蔡燕军,项美香..急性冠状动脉综合征患者BNP水平及其影响因素分析[J].浙江医学,2014,(16):1395-1397,3.
