浙江医学Issue(20)：1674-1676,1680,4.
不同麻醉及镇痛方法对肺癌根治术患者细胞免疫功能的影响
Effect of different methods of anesthesia and analgesia on cellular immune function in lung cancer surgery patients
摘要
Abstract
Objective To investigate the effect of two different methods of anesthesia and analgesia on cellular immune function in patients underwent radical resection of pulmonary carcinoma. Methods Forty patients underwent elective thoraco-tomy lung cancer surgery were randomly divided into two groups. Patients were implemented either total intravenous anesthesia combined with intravenous analgesia (group A)or general anesthesia combined with epidural anesthesia and post- op- epidural analgesia (group B). T cellsubsets and NK cellfunction were compared within 72h after surgery. Results Except for the in-crease of CD8+ (P<0.01), postoperative CD3+,CD4+and NK cellwere decreased (P<0.05 or 0.01) in both groups.The indices recovered to the pre- op level in group B 72h after surgery(P>0.05),but not in group A. Conclusion General anesthesia com-bined with epidural anesthesia and post- op epidural analgesia might be an effective anesthesia method with faster recovery and minor interference on the immune function of lung cancer patients.关键词
全身麻醉/硬膜外麻醉/硬膜外镇痛/细胞免疫Key words
General anesthesia/Epidural anesthesia/Epidural analgesia/Cellular immunity引用本文复制引用
朱韵甜,陈亦蛟,周大春..不同麻醉及镇痛方法对肺癌根治术患者细胞免疫功能的影响[J].浙江医学,2014,(20):1674-1676,1680,4.基金项目
浙江省自然科学基金 （）
