浙江医学Issue(5)：375-376,380,3.
桥本甲状腺炎合并甲状腺癌的危险因素回归分析
Risk factors associated with Hashimoto's thyroiditis with thyroid cancer
季晓春 1黄春军 1彭莹莹1
作者信息
- 1. 315040 宁波市医疗中心李惠利医院普外科
- 折叠
摘要
Abstract
Objective To assess the risk factors associated with Hashimoto's thyroiditis (HT) with thyroid cancer. Meth-ods Fifty nine HT patients complicated with thyroid cancer (case group) and 118 HT patients or HT patients with benign thyroid nodule (control group) matched by 1:2 were selected in the study. Chi- square test, Fisher exact probabilities, t test, univariate and multivariate logistic regression were used to analyze the data. Results Univariate analysis showed that family history, high iodine intake, history of radiation exposure, autoantibody status and merger of solitary thyroid nodules were risk factors related to HT with thyroid cancer. Multivariate conditional logistic regression analysis showed that family history (OR=2.141, 95%CI:1.664~2.755), high iodine intake(OR=2.479, 95%CI:1.895~2.936) , history of radiation exposure (OR=4.596, 95%CI:3.693~4.997) were independent risk factors for HT with thyroid cancer. Conclusion The study shows that family history, high iodine intake and history of radiation exposure are risk factors for occurrence of thyroid cancer in patients with Hashimoto's thyroiditis.关键词
桥本甲状腺炎/甲状腺癌/病例对照/危险因素Key words
HT/Thyroid cancer/Case- control study/Risk factors引用本文复制引用
季晓春,黄春军,彭莹莹..桥本甲状腺炎合并甲状腺癌的危险因素回归分析[J].浙江医学,2015,(5):375-376,380,3.
