肿瘤药学Issue(6):410-414,5.DOI:10.3969/j.issn.2095-1264.2014.085
上皮间质转化与乳腺癌
Epithelial Mesenchymal Transition and Breast Cancer
张艳敏(综述) 1梁路昌 1杨心治 1钟警 1文格波(审校)1
作者信息
- 1. 南华大学附属第一医院,湖南衡阳,421001
- 折叠
摘要
Abstract
Breast cancer is one of the most common tumors in women. The main causes of reappear and even death of breast cancer patients were the tumor invasion and metastasis. Epithelial Mesenchymal Transition (EMT) is a proc-ess of tumor cell phenotypic changes. The unusual combination of EMT with stem cells competence might result in the production of tumor stem cells and enhance the capacity of tumour cell invasion, migration and metastasis. As a result, EMT can be served as a new approach for the study of breast cancer. It also could provide new targets for the treatment of breast cancer. In this paper, we mainly reviewed the research progress of EMT and breast cancer.关键词
上皮-间质细胞转化/肿瘤侵袭/肿瘤转移/乳腺癌Key words
Epithelial Mesenchymal Transition/Tumor invasion/Tumor metastasis/Breast Cancer分类
医药卫生引用本文复制引用
张艳敏(综述),梁路昌,杨心治,钟警,文格波(审校)..上皮间质转化与乳腺癌[J].肿瘤药学,2014,(6):410-414,5.