肿瘤药学Issue(1)：42-45,4.DOI:10.3969/j.issn.2095-1264.2015.007
联合检测结直肠癌术前血清CA199、CEA对预后评估的作用
The Value of Joint Detection of Serum CA199 and CEA before Operation for Prognosis Evaluation of Colorectal Cancer Patients
茅力平 1沈飞 1孙雅君 1刘振宗 1沈萍1
作者信息
- 1. 南通市老年康复医院肿瘤科，江苏南通，226001
- 折叠
摘要
Abstract
ObjectiveToinvestigatethevalueoftheprognosisevaluationsofjointdetectionofserumCA199andCEA before operation for the prognosis evaluation of colorectal cancer patients.Methods Serums were collected from 126 patients with colorectal cancer before operation. Immunoassay was employed to determine their CA199 and CEA contents. Accord-ing to the results, the patients were classified into four groups:CA199(-)/CEA(-), CA199(-)/CEA(+), CA199(+)/CEA(-) and CA199(+)/CEA(+). Their clinical stages and survival time were compared. Results CA199(+) was related to tumor infiltrat-ing degree, lymph node metastasis and stage, and when compared with CA199(-), differences were statistically significant (P<0.05). The patients' survival time in CA199(+)/CEA(+) group was much shorter than in the other three groups. The patients' survival time in CA199(+)/CEA(-) group was shorter than in CA199(-)/CEA(+) group (P<0.05). Conclusion De-tection of serum before colorectal cancer operation, CA199 positive patients have shorter survival time than CEA positive patients, and CA199(+)/CEA(+) patients would have even poorer prognosis. It is important to pay attention to the prognosis of CA199 positive patients.关键词
结直肠癌/糖类抗原199/癌胚抗原/预后Key words
Colorectalcancer/CA199/CEA/Prognosis分类
医药卫生引用本文复制引用
茅力平,沈飞,孙雅君,刘振宗,沈萍..联合检测结直肠癌术前血清CA199、CEA对预后评估的作用[J].肿瘤药学,2015,(1):42-45,4.
