肿瘤药学Issue(2):83-86,4.DOI:10.3969/j.issn.2095-1264.2015.016
具核梭杆菌与大肠肿瘤发生发展的研究进展
The Relationship between Fusobacterium Nucleatum and the Development of Colorecal Neoplasia
摘要
Abstract
The effects of gut microbiota on colorectal tumor attract widespread attention. Fusobacterium nucleatum (Fn), a com-mensal resident of the human gut, is closely associated with intestinal tumorigenesis. Fn may contribute to the development and prognosis of colorectal cancer. Studies of clinical epidemiology and molecular mechanisms on this topic provide new ideas for the pre-vention and the treatment of colorectal cancer. The present article summaries the recent advances in the relationship between Fn and the development of colorecal neoplasia, and outlines the future prospect.关键词
大肠肿瘤/具核梭杆菌/分子机制Key words
Colorectal tumor/Fusobacterium nucleatum/Molecular mechanisms分类
医药卫生引用本文复制引用
窦燕,曹海龙,许梦雀,鄢芳,王邦茂..具核梭杆菌与大肠肿瘤发生发展的研究进展[J].肿瘤药学,2015,(2):83-86,4.基金项目
国家自然科学基金资助项目(81470796,81300272)。 ()