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具核梭杆菌与大肠肿瘤发生发展的研究进展

窦燕 曹海龙 许梦雀 鄢芳 王邦茂

肿瘤药学Issue(2):83-86,4.
肿瘤药学Issue(2):83-86,4.DOI:10.3969/j.issn.2095-1264.2015.016

具核梭杆菌与大肠肿瘤发生发展的研究进展

The Relationship between Fusobacterium Nucleatum and the Development of Colorecal Neoplasia

窦燕 1曹海龙 1许梦雀 1鄢芳 1王邦茂1

作者信息

  • 1. 天津医科大学总医院消化内科,天津,300052
  • 折叠

摘要

Abstract

The effects of gut microbiota on colorectal tumor attract widespread attention. Fusobacterium nucleatum (Fn), a com-mensal resident of the human gut, is closely associated with intestinal tumorigenesis. Fn may contribute to the development and prognosis of colorectal cancer. Studies of clinical epidemiology and molecular mechanisms on this topic provide new ideas for the pre-vention and the treatment of colorectal cancer. The present article summaries the recent advances in the relationship between Fn and the development of colorecal neoplasia, and outlines the future prospect.

关键词

大肠肿瘤/具核梭杆菌/分子机制

Key words

Colorectal tumor/Fusobacterium nucleatum/Molecular mechanisms

分类

医药卫生

引用本文复制引用

窦燕,曹海龙,许梦雀,鄢芳,王邦茂..具核梭杆菌与大肠肿瘤发生发展的研究进展[J].肿瘤药学,2015,(2):83-86,4.

基金项目

国家自然科学基金资助项目(81470796,81300272)。 ()

肿瘤药学

OACSTPCD

2095-1264

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