中南民族大学学报（自然科学版）Issue(3)：37-40,4.
MMP3基因启动子rs102715950（5A／6A）单核苷酸多态性与河南人群食管鳞癌易感性的关系
Association between SNP rs102715950(5A/6A) of MMP3 Gene and Susceptibility to Esophageal Squamous Cell Carcinoma in Different Groups of People in Henan
摘要
Abstract
To explore the association between SNP rs 102715950(5A/6A) in 5′-end regulation region of MMP3 gene and susceptibility to esophageal squamous cell carcinoma ( ESCC ) in different groups of people in Henan , Genomic DNA was extracted from peripheral blood with the proteinase K method .The genotyping was carried out by PCR-RFLP and analyzed comparatively.Then the results of genotyping were analyzed by SPSS 19.0.The results showed that there was no statistical differences in the genotyping of MMP3 SNP rs102715950(5A/6A) of among 3 groups of people ,including sporadic cases of esophageal cancer , migrants of the high incidence area and healthy controls in Henan .So there was no obvious correlations between the MMP3 SNP rs102715950(5A/6A) with the susceptibility of esophageal squamous cell carcinoma among the people in Henan .关键词
MMP3基因SNP/河南不同人群/基因分型/PCR-RFLP/logitic回归分析Key words
MMP3/SNP/genotyping/ESCC/different groups of Henan people分类
生物科学引用本文复制引用
李劲,李可可,姚品芳,陈静波,陈真..MMP3基因启动子rs102715950（5A／6A）单核苷酸多态性与河南人群食管鳞癌易感性的关系[J].中南民族大学学报（自然科学版）,2014,(3):37-40,4.基金项目
武汉市科技计划项目攻关计划资助项目 （）
