中国现代医生Issue(14)：12-15,4.
非肥胖2型糖尿病合并非酒精性脂肪性肝病危险因素及与并发症的相关性研究
Risk factors and complications of non-obese type 2 diabetes mellitus with nonalcoholic fatty liver disease
摘要
Abstract
Objective To study the risk factors and complications of non-obese type 2 diabetes mellitus with nonalco-holic fatty liver disease. Methods A total of 428 cases of non-obese type 2 diabetic patients were divided into groups of non-alcoholic fatty liver disease (NAFLD group) of 193 cases and non-NAFLD group of 235 cases, compare living index, physical indicators, general information and chronic complications rate of type 2 diabetes risk factors for NAFLD of two groups. Results NAFLD peripheral blood HbA1C, FINS, C peptide, HOMA-IR, TC, TG, LDL-C, ALT, AST, UA levels were significantly higher than non-NAFLD group (P <0.05), AST/ALT ratio were significantly lower in non-NAFLD group (P<0.05). NAFLD group BMI, waist-hip ratio were significantly higher than non-NAFLD group (P <0.05). Included HOMA-IR, TG, LDL-C, waist-hip ratio were type 2 diabetes mellitus with nonalcoholic fatty liver disease risk factors (P <0.05). NAFLD group diabetic nephropathy,hypertension,atherosclerosis,coronary heart disease, cerebrovascular disease incidence were significantly higher than non-NAFLD group(P <0.05). Conclu-sion Insulin resistance, dyslipidemia and fat maldistribution and non-obese type 2 diabetic patients with NAFLD re-lated chronic complications in patients with NAFLD increased incidence.关键词
2型糖尿病/非酒精性脂肪性肝病/危险因素/并发症,慢性/胰岛素抵抗Key words
Type 2 diabetes/Non-alcoholic fatty liver disease/Risk factors/Complications/Chronic/Insulin resis-tance分类
医药卫生引用本文复制引用
袁春钢,黄翯..非肥胖2型糖尿病合并非酒精性脂肪性肝病危险因素及与并发症的相关性研究[J].中国现代医生,2014,(14):12-15,4.基金项目
国家自然科学基金 （）
