中国现代医生Issue(20):41-43,3.
阿戈美拉汀与帕罗西汀治疗老年抑郁症对照研究
A control study on agomelatine and paroxetine in treatment of senile de-pression
于志军 1么宪伟 2潘红珊 2莫翠英 2段新 2李春阳3
作者信息
- 1. 广东省佛山市顺德区伍仲珮纪念医院药械科,广东佛山 528300
- 2. 广东省佛山市顺德区伍仲珮纪念医院老年综合科,广东佛山 528300
- 3. 广东省佛山市顺德区伍仲珮纪念医院科教科,广东佛山 528300
- 折叠
摘要
Abstract
Objective To compare the clinical efficacy and safety of agomelatine and paroxetine for the senile depression. Methods A total of 98 cases of elderly patients diagnozed with depression were randomly divided into two groups, one group were treated with agomelatine,the other group were treated with paroxetine,treated for 6 weeks, using Hamilton depression scale(HAMD), adverse reaction scale(TESS) to evaluate the efficacy and adverse reactions. Results After 6 weeks of treatment, the HAMD scores showed that there were no significant differences in clinical efficacy of two groups, and the TESS showed the agomelatine had less adverse reaction than the paroxetine. Conclusion Agomelatine is a safe and effective antidepressant , suitable for elderly patients.关键词
阿戈美拉汀/帕罗西汀/老年抑郁症Key words
Agomelatine/Paroxetine/Senile depression分类
医药卫生引用本文复制引用
于志军,么宪伟,潘红珊,莫翠英,段新,李春阳..阿戈美拉汀与帕罗西汀治疗老年抑郁症对照研究[J].中国现代医生,2014,(20):41-43,3.