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三叶青提取物诱导人宫颈癌Hela细胞凋亡的研究

李萍 彭昕

中国现代医生Issue(23):4-6,9,4.
中国现代医生Issue(23):4-6,9,4.

三叶青提取物诱导人宫颈癌Hela细胞凋亡的研究

Investigation on apoptosis of human cervical cancer Hela cells induced by extracts from tetrastigma hemsleyanum diels et gilg

李萍 1彭昕2

作者信息

  • 1. 宁波市鄞州人民医院病理科,浙江宁波 315000
  • 2. 浙江医药高等专科学校,浙江宁波 315100
  • 折叠

摘要

Abstract

Objective To study the effect of extracts from tetrastigma hemsleyanum diels et gilg on the proliferation of human cervical cancer Hela cells. Methods MTT assay was used to determine the inhibitory rate of the extracts from tetrastigma hemsleyanum diels et gilg on the proliferation of HeLa cells. The morphology of cell apoptosis was observed by inverted microscope. Results The inhibition ratio of tumor cell was gradually increased with the longer extension time or the increase of dosages of the extracts from tetrastigma hemsleyanum diels et gilg the treatment groups was significant differentce(P<0.05) compared with the control group. Under inverted microscope, the tumor cells showed a special phenomenon of cellular apoptosis. Conclusion The extracts of tetrastigma hemsleyanum diels et gilg has a significant toxicological effect on human cervical cancer Hela cells, which positively relates with its concentration and effect time.

关键词

三叶青/Hela细胞/诱导凋亡/MTT法

Key words

Tetrastigma hemsleyanum diels et gilg/Hela cells/Apoptosis-inducing/MTT assay

分类

医药卫生

引用本文复制引用

李萍,彭昕..三叶青提取物诱导人宫颈癌Hela细胞凋亡的研究[J].中国现代医生,2014,(23):4-6,9,4.

基金项目

浙江省中医药科技计划A类资助课题 ()

中国现代医生

1673-9701

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