摘要
Abstract
Objective To observe the effect of amlodipine and atorvastatin calcium in threatment of patients with hy-pertension and the impact on tumor necrosis factor and interleukin-6. Methods A total of 80 patients with essential hypertension were randomly divided into observation group and control group, each of 40 cases, observation group was given amlodipine and atorvastatin calcium therapy, the control group was given amlodipine treatment groups, efficacy and TNF-αand IL-6 were compared before and after treatment in two groups. Results After 2 months of treatment, the total effective rate of observation group was 92.5%, significantly higher than the control group (92.5% vs 77.5%, P<0.05). Observation group’s SBP, DBP, HR was significantly lower than the control group (P<0.05).After treatment,the TNF-α, IL-6 level of observation group was significantly lower than the control group(P<0.05). Conclusion Amlodip-ine and atorvastatin calcium in treatment of essential hypertension can improve efficacy, worthy of clinical application .关键词
氨氯地平/阿托伐他汀钙/原发性高血压/肿瘤坏死因子/白介素-6Key words
Amlodipine/Atorvastatin calcium/Essential hypertension/Tumor necrosis factor/Interleukin-6分类
医药卫生
