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血清学无创肝纤维化检测与肝脏穿刺病理诊断的比较研究

王玲娣 巫露丹 毛卫林

中国现代医生Issue(24):90-92,3.
中国现代医生Issue(24):90-92,3.

血清学无创肝纤维化检测与肝脏穿刺病理诊断的比较研究

comparative study of non-invasive fibrosis serological testing and liver biopsy diagnosis of liver

王玲娣 1巫露丹 2毛卫林3

作者信息

  • 1. 宁波市鄞州人民医院病理科,浙江宁波 315040
  • 2. 宁波市李惠利医院检验科,浙江宁波 315040
  • 3. 浙江大学医学院附属第一医院检验科,浙江杭州 310003
  • 折叠

摘要

Abstract

Objective To compare the serological non-invasive liver fibrosis tests and pathological examination in the clinical diagnosis of chronic hepatitis B. Methods Selected 97 patients with chronic hepatitis B in our hospital as the research object and tested non-invasive liver fibrosis tests and liver biopsy pathological examination.Compare the test results of two kinds. Results The serum noninvasive hepatic fibrosis index(PⅢP,Ⅳ-C,HA,LN)showed good positive correlation with pathological stage. The correlation coefficient suggested that with the aggravation of hepatic fibrosis,liv-er fibrosis indexes tended to rise gradually,and the indicators differences were statistically significant (P<0.05). Con-clusion Liver biopsy in patients with chronic hepatitis B diagnosis detection is the "gold standard" with greater injury. Serological non-invasive liver fibrosis tests has high diagnostic value,can reduce the number of puncture biopsy.

关键词

慢性乙型肝炎/肝纤维化/穿刺病理/血清学

Key words

Chronic hepatitis B/Liver fibrosis/Pathology/Serology

分类

医药卫生

引用本文复制引用

王玲娣,巫露丹,毛卫林..血清学无创肝纤维化检测与肝脏穿刺病理诊断的比较研究[J].中国现代医生,2014,(24):90-92,3.

基金项目

浙江省医药卫生科技计划 ()

中国现代医生

1673-9701

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