中国现代医生Issue(29):16-18,3.
甘露聚糖肽联合奈达铂治疗恶性胸腔积液疗效观察
Therapeutic effect of mannatide injection and nedaplatin on malignant pleural effusion
何松林 1刘慧 2赵泽良 1李霄1
作者信息
- 1. 川北医学院附属医院胸心外科,四川南充 637001
- 2. 川北医学院附属医院心内科,四川南充 637001
- 折叠
摘要
Abstract
Objective To observe the efficacy of mannatide injection and nedaplatin injected in thoracic cavity in the treatment of malignant pleural effusion. Methods Ninety-four patients with malignant pleural effusion were randomly divided into two groups. The observation group of 48 patients were given mannatide injection and nedaplatin,and con-trol group of 46 patients were given only nedaplatin. Effectiveness and adverse reactions were observed after treatment. Results The effective rate was 85.4% in observation group, hihger than that in control group (69.6%)(P<0.05); The incidence rates of gastrointestinal tract and bone marrow and chest pain of observation group were 35.4%,22.9% and 18.8%. Compared with control group, the incidence of observation group had significantly lowered. There were signifi-cant differences between the two groups(P<0.05). Conclusion Mannatide injection combined with nedaplatin is more efficient and less adverse reaction for malignant pleural effusion, so it is worth popularizing.关键词
甘露聚糖肽/奈达铂/恶性胸腔积液Key words
Mannatide Injection/Nedaplatin/Malignant pleural effusion分类
医药卫生引用本文复制引用
何松林,刘慧,赵泽良,李霄..甘露聚糖肽联合奈达铂治疗恶性胸腔积液疗效观察[J].中国现代医生,2014,(29):16-18,3.