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难治性幻听患者应用rTMS治疗后幻听评分及血清BDNF水平的变化及意义

陶云海

中国现代医生Issue(29):28-30,34,4.
中国现代医生Issue(29):28-30,34,4.

难治性幻听患者应用rTMS治疗后幻听评分及血清BDNF水平的变化及意义

Changes and significance of auditory hallucinations score and serum BDNF levels of refractory auditory hallucinations patients after rTMS therapy

陶云海1

作者信息

  • 1. 杭州市第七人民医院神经科,浙江杭州 310013
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摘要

Abstract

Objective To investigate the changes and significance of auditory hallucinations score and serum BDNF levels of refractory auditory hallucinations patients after rTMS therapy. Methods Fifty cases of patients with refractory auditory hallucinations who were treated in our hospital from 2011 to 2013 were selected. These patients were divided into observation group and control group according to a random number table, 25 cases in each group. The patients in control group were given pseudo-rTMS stimulation therapy, while the observation group were given true rTMS stimula-tion therapy, then the auditory hallucinations score, serum BDNF levels of the two groups of patients were analyzed. Results After treatment, the auditory hallucinations score of the observation group was significantly lower (P<0.05); the serum BDNF levels after 2,4 weeks treatment of the observation group were significantly higher than those of the control group (P<0.05). Conclusion True rTMS stimulation therapy is more effective to enhance patient's BDNF lev-els, thereby greatly improve the auditory hallucinations than pseudo-rTMS stimulation therapy in the treatment of re-fractory auditory hallucinations patients.

关键词

难治性幻听/rTMS/幻听评分/血清BDNF水平

Key words

Refractory auditory hallucinations/rTMS/Auditory hallucinations score/Serum BDNF levels

分类

医药卫生

引用本文复制引用

陶云海..难治性幻听患者应用rTMS治疗后幻听评分及血清BDNF水平的变化及意义[J].中国现代医生,2014,(29):28-30,34,4.

基金项目

浙江省医药卫生科技计划项目 ()

中国现代医生

1673-9701

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