中国现代医生Issue(29)：132-133,136,3.
CIK细胞免疫治疗对转移性肾细胞癌患者免疫功能的影响
Effect of CIK cells immunotherapy on immunological function of patients with metastatic renal cell carcinoma
崔洪泉 1赵俊峰 1李保东 2张林超3
作者信息
- 1. 河南省中医院泌尿外科，河南郑州 450002
- 2. 河南省肿瘤医院泌尿外科，河南郑州 450008
- 3. 郑州市中心医院泌尿外科，河南郑州 450000
- 折叠
摘要
Abstract
Objective To study the effect of cytokine-induced killer(CIK) cells immunotherapy on immunological func-tion of patients with metastatic renal cell carcinoma.Methods A total of 70 patients with metastatic renal cell carcino-ma were randomly divided into 2 groups, 35 cases of the treatment group were added with CIK cells, while the control group was given IL-2 and IFN-α, detected the immunological function of 70 cases including the levels of CD3+, CD4+, CD8+T cells, ratio of CD4+/CD8+, one week before therapy of CIK cells and one month week after treatment. Results The levels of CD3+、CD4+cells, ratio of CD4+/CD8+in peripheral blood of patients with renal cancer of two groups were much higher than those before therapy (P<0.05), the levels CD8+ was lower after treatment, there were significant changes (P<0.05). Conclusion CIK cells immunotherapy can enhance the immunological function of patients with meta-static renal cell carcinoma.关键词
CIK细胞/转移性肾细胞癌/免疫功能Key words
CIK cells/Metastatic renal cell carcinoma/Immunological function分类
医药卫生引用本文复制引用
崔洪泉,赵俊峰,李保东,张林超..CIK细胞免疫治疗对转移性肾细胞癌患者免疫功能的影响[J].中国现代医生,2014,(29):132-133,136,3.
