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中医辨证分型与慢性乙型肝炎患者T淋巴细胞亚群及VCS参数的关系

袁满春 赵锋 刘志伟 杨敏春

中国现代医生Issue(30):58-60,63,4.
中国现代医生Issue(30):58-60,63,4.

中医辨证分型与慢性乙型肝炎患者T淋巴细胞亚群及VCS参数的关系

The association of T lymphocyte subsets and VCS parameters with differ-ent syndrome types in patients with chronic hepatitis B patients

袁满春 1赵锋 2刘志伟 2杨敏春3

作者信息

  • 1. 浙江省嵊州人民医院检验科,浙江嵊州 312400
  • 2. 浙江大学医学院附属邵逸夫医院检验科,浙江杭州 310016
  • 3. 浙江大学医学院附属邵逸夫医院中医科,浙江杭州 310016
  • 折叠

摘要

Abstract

Objective To investigate the changes of T cell subsets VCS caused by different syndrome types in patients with Chronic Hepatitis B (CHB). Methods A total of 116 samples were enrolled in the study, which were divided into 3 groups:43 CHB patients of liver depressions and spleen deficiency type, 38 of damp-heat type and 35 of blood stasis type. 48 healthy people were also included as normal control. ALT, WBC, CD4+, CD8+, CD4+/CD8+, MLV, MLV-SD, MLC, MLC-SD, MLS and MLS-SD of the 4 groups were tested and analyzed. Results ALT, CD8+, MLV, MLV-SD, MLC-SD and MLS-SD of CHB patients of liver depression and spleen deficiency type, damp-heat type and blood stasis type were significantly increased compared with normal group (P<0.05), however, WBC, CD4+, CD4+/CD8+, MLC and MLS were decreased apparently (P<0.05). CD8+, MLV-SD, MLC-SD, MLS and MLS-SD were significantly different between damp-heat type and liver depressions and spleen deficiency type (P<0.05). ALT, CD4+, CD8+, CD4+/CD8+, MLV, MLV-SD, MLC-SD and MLS were distinct between damp-heat type and blood stasis type (P<0.05). Conclusion T cell subsets and VCS parameters were varied in different CHB syndrome types, suggesting that correlations exited a-mong T cell subsets, VCS parameters and syndrome type of CHB, which may provide useful information for Chinese medicine dialectical sub-typing of CHB.

关键词

中医辨证分型/慢性乙型肝炎/T淋巴细胞亚群/VCS参数

Key words

Chinese medicine dialectical sub-typing/Chronic hepatitis B/T cell subsets/VCS parameters

分类

医药卫生

引用本文复制引用

袁满春,赵锋,刘志伟,杨敏春..中医辨证分型与慢性乙型肝炎患者T淋巴细胞亚群及VCS参数的关系[J].中国现代医生,2014,(30):58-60,63,4.

基金项目

浙江省教育厅科研项目 ()

中国现代医生

1673-9701

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