摘要
Abstract
Objective To explore the relationship between the serum procalcitonin(PCT) level and liver function in pa-tients with hepatitis and liver cirrhosis. Methods A retrospective analysis of 80 cases of hepatitis B virus in our hospi-tal from December 2012 to December 2013 admitted (hepatitis B virus, HBV) infection in patients with hepatitis and liver cirrhosis, included acute hepatitis B (acute hepatitis B, AHB) infection in 20 patients and hepatic cirrhosis (hep-atic cirrhosis, HC) infection in 60 patients. PCT in peripheral blood, white blood cell count, neutrophil count and liver function tests (ALT, AST, TBIL, PTA) levels before and after treatments in patients, and the relationship between PCT and liver function of patients were evaluated. Results PCT level, white blood cell count and neutrophil count in AHB patients and HC patients before treatment were significantly higher than that after treatment, there was statistically sig-nificant difference (t=11.411, 2.217, 3.567, P<0.05); After treatment, patients liver function was significantly improved than before treatment, the difference was statistically significant (t=14.465, 13.164, 14.563, 8.579, P<0.05);The level of PCT in serum and liver function of ALT, AST, TBIL were positively correlated, negatively correlated with the level of PTA (r=0.877, 0.964, 0.859, -0.744, P<0.05). Conclusion There is correlation between PCT level and each index in patients with hepatitis B virus infection and liver cirrhosis, which have significance in treatment patients with infection and liver function disorder.关键词
肝炎/肝硬化/降钙素原/肝功能/关系Key words
Hepatitis/Liver cirrhosis/Procalcitonin/Liver function/Relationship分类
医药卫生