摘要
Abstract
Objective To evaluate the efficacy of epidural dexmedetomidine (Dex) and sufentanil on ropivacaine epidu-ral anesthesia. Methods A total of 120 cases of ASA Ⅰ to Ⅱ patients used epidural anesthesia with ropivacaine for lower limb orthopedic surgery were randomly allocated into epidural anesthesia with ropivacaine+normal saline group, ropivacaine+sufentanil group, ropivacaine+dexmedetomidine group, the hemodynamic changes, sensory block onset time, the highest plane of sensory block, sensory block continuous time, completed motor block time before and after anesthe-sia drugs and occurrence of adverse reaction of nausea, itching, vomiting were observed. Results The sensory block on-set time, complete motor block time in the dexmedetomidine group were shorter than the other two groups, with signifi-cant difference (t=4.25, 4.59, 4.32, 3.82, 3.79, 4.23, P<0.05); The duration of sensory block was higher than that in the other two groups, with significant difference (t=6.24, 5.78, P<0.05); Hemodynamic changes and adverse reaction rate in each group had no significant difference (P>0.05). Conclusion Epidural DEX can enhance the epidu ral anesthesia effect of ropivacaine than sufentanil effectively, and it does not increase the incidence of adverse reaction.关键词
右美托咪定/舒芬太尼/硬膜外麻醉/罗哌卡因Key words
Dexmedetomidine/Remifentanil/Epidural anesthesia/Ropivacaine分类
医药卫生
