中国现代医生Issue(10)：33-35,39,4.
氧驱动雾化吸入重组人干扰素-α2a注射液治疗婴幼儿毛细支气管炎的疗效观察
Observation of curative effects of oxygen-driven atomized inhalation of recombinant human interferon-α2a injection in the treatment of infantile capillary bronchitis
王国权 1吴晓兰 2邹富梅3
作者信息
- 1. 江西省永新县人民医院儿科，江西永新 343400
- 2. 江西省永新县人民医院护理部，江西永新 343400
- 3. 江西省永新县卫生局，江西永新 343400
- 折叠
摘要
Abstract
Objective To explore the clinical effects of oxygen-driven atomized inhalation of recombinant human inter-feron-α2a injection in the treatment of infantile capillary bronchitis. Methods 240 infant patients with capillary bron-chitis were assigned to a control group and a treatment group according to their disease conditions, with 120 patients in each group. The control group received regular treatment(oxygen uptake, atomized inhalation of pulmicort respulas+nebulized terbutaline sulphate solution used for anti-inflammation and antiasthma, aspiration of sputum, antibiotics giv-en to infants suspected to be complicated with bacterial infection, intravenous drip of methylprednisolone given to in-fants with severe symptoms, etc.); The treatment group further received oxygen-driven atomized inhalation of 600,000 international units of recombinant human interferon-α2a injection, once a day for 5 days. Clinical effects and main ob-servational indices between the two groups were compared. Results Total effective rate was 95.0% in the treatment group and 78.3%in the control group, and the differences between the two groups were statistically significantly(P<0.05). Alleviating time of asthma, disappearing time of lung rale, time of persistent cough and hospitalization time in the treatment group were all lower than those in the control group, and the differences between the two groups were statisti cally significant (P<0.05). Significant adverse events were not detected during the treatment period of oxygen-driven atomized inhalation of recombinant human interferon-α2a injection applied by the infant patients. Conclusion Oxygen-driven atomized inhalation of recombinant human interferon-α 2a injection in the treatment of infantile capillary bron-chitis has an exact curative effect, and it is safe, which is worthy of clinical pediatric promotion and application.关键词
重组人干扰素-α2a注射液/氧气驱动/雾化吸入/婴幼儿毛细支气管炎Key words
Recombinant human interferon-α 2a injection/Oxygen driven/Atomization inhalation/Bronchiolitis of infants分类
医药卫生引用本文复制引用
王国权,吴晓兰,邹富梅..氧驱动雾化吸入重组人干扰素-α2a注射液治疗婴幼儿毛细支气管炎的疗效观察[J].中国现代医生,2015,(10):33-35,39,4.
