中国现代医生Issue(14)：100-102,112,4.
同型半胱氨酸、糖化血红蛋白和尿微量白蛋白联合检测对早期糖尿病肾损伤的诊断价值
Value of homocysteine, glycosylated hemoglobin and urine albumin com-bined detection in diagnosis of early diabetic renal injury
摘要
Abstract
Objective To investigate the value of homocysteine, glycosylated hemoglobin and urine albumin combined detection in diagnosis of early diabetic renal injury. Methods All 40 patients with early renal disease in our hospital,data were analyzed, set the experiment group and 40 patients in our hospital at the same time were selected as the healthy control group, used cyclic enzymatic detection Hcy, ion exchange liquid chromatography HbA1c, the rate of scattering assay used U-mAlb, comparing two groups of homocysteine, gly cosylated hemoglobin and urine albumin and other indicators. Results The serum Hcy levels(23.71±1.91)μmol/L,HbA1c levels(10.01±2.53)%,U-mAlb level(263.34±6.23)mg/L in experiment group was significantly higher than the control group(P<0.05);Hcy abnormal blood test group was 70%, HbA1c anomaly detection rate of 60%, U-mAlb level anomaly detection rate of 57.5%, signifi cantly higher (blood Hcy, HbA1c and urine abnormality U-mAlb detection rate was 0%)(P<0.05); early diabetes diagnosis using U-mAlb positive rate of 42.5%, Hcy joint U-mAlb positive rate was 70.0%, HbA1c joint U-mAlb positive rate of 67.5%, Hcy joint HbA1c joint U-mAlb positive rate was 82.5%. Conclusion Homocysteine, glycosy-lated hemoglobin and urine albumin ideal joint detection of early diagnosis of diabetic renal injury results,the positive rate of detection can be improved and should be introduced.关键词
同型半胱氨酸/糖化血红蛋白/尿微量白蛋白/早期糖尿病肾病损伤Key words
Homocysteine/Glycated hemoglobin/Microalbuminuria/Early diabetic nephropathy injury分类
医药卫生引用本文复制引用
余爱萍,孙晶..同型半胱氨酸、糖化血红蛋白和尿微量白蛋白联合检测对早期糖尿病肾损伤的诊断价值[J].中国现代医生,2015,(14):100-102,112,4.基金项目
浙江省公益性技术应用研究计划项目 （）
