中国现代医生Issue(14)：156-160,5.
克唑替尼抗肿瘤的研究进展
Research progress in anti-turmor of Crizotinib
陈少波 1张厚德1
作者信息
- 1. 广东医学院附属南山医院消化内科，广东深圳 518000
- 折叠
摘要
Abstract
Crizotinib is effective to treat non small cell lung cancer, the study has found that it can inhibit the prolif-eration of tumor cells, induce tumor cells apoptosis and inhibit tumor cells invade and transfer. Crizotinib anti-tumor effect involving the anaplastic lymphoma kinase, HGF/c-MET signaling pathway, c-ros oncogene 1 receptor tyrosine kinase, Bim gene, mammalian target of rapamycin, hypoxia induced factor-1, the clinical treatment has found that crizotinib appear resistance in recent years, so its anti-tumor and drug resistance mechanism still need further study in the furture.关键词
克唑替尼/抗肿瘤Key words
Crizotinib/Anti-tumor分类
医药卫生引用本文复制引用
陈少波,张厚德..克唑替尼抗肿瘤的研究进展[J].中国现代医生,2015,(14):156-160,5.
